Description

5-Bromo-1,4,6-Trimethyl-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the design of new drug candidates.
• Kinase Inhibitor Development: Used in the research and production of targeted kinase inhibitors due to its privileged heterocyclic core.
• Chemical Synthesis Building Block: Enables the introduction of the bromo-substituted pyrrolopyridine moiety into more complex molecular architectures.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents.
• Material Science Exploration: Investigated for use in the synthesis of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	5-Bromo-1,4,6-Trimethyl-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	627098-12-8
Molecular Formula	C11H13BrN2
Molecular Weight	253.14 g/mol
Synonyms	5-Bromo-1,4,6-trimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-2,3-dihydro-1,4,6-trimethyl-; 627098-12-8; 5-Bromo-1,4,6-trimethyl-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine; 5-Bromo-1,4,6-trimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-1,4,6-Trimethyl-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.