Description

1H-Pyrrolo[2,3-B]Pyridine-3-Acetic Acid, A-Oxo-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine core structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex nitrogen-containing heterocycles in medicinal chemistry.
• Biochemical Research: Employed in academic and industrial R&D for probing biological pathways and enzyme functions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials due to its conjugated system.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Acetic Acid, A-Oxo-, Ethyl Ester
CAS No.	626604-80-6
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	Ethyl 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-2-oxoacetate; 2-Oxo-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid ethyl ester; 1H-Pyrrolo[2,3-b]pyridine-3-glyoxylic acid ethyl ester; 3-(Ethoxyoxalyl)-1H-pyrrolo[2,3-b]pyridine; 626604-80-6; Pyrrolo[2,3-b]pyridine-3-acetic acid, α-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Acetic Acid, A-Oxo-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.