Description

7'-Bromo-2',3'-dihydro-1'H-spiro[cyclohexane-1,4'-isoquinoline] is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for the synthesis of novel bioactive molecules targeting central nervous system disorders. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for neurological and psychiatric applications.

Application

• Key Intermediate in Drug Discovery: Serves as a critical building block for the synthesis of potential drug candidates with spirocyclic architectures.
• Neurological Research: Used in the development of compounds targeting receptors and enzymes associated with neurodegenerative diseases and psychiatric conditions.
• Medicinal Chemistry Libraries: Incorporated into screening libraries to explore new chemical space and identify lead compounds with improved pharmacological profiles.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and novel synthetic methodologies.

Basic Information

Product Name	7'-Bromo-2',3'-dihydro-1'H-spiro[cyclohexane-1,4'-isoquinoline]
CAS No.	626603-70-1
Molecular Formula	C14H16BrN
Molecular Weight	278.19 g/mol
Synonyms	7'-Bromospiro[cyclohexane-1,4'-isoquinoline]; 1'H-Spiro[cyclohexane-1,4'-isoquinoline], 7'-bromo-2',3'-dihydro-; 7'-Bromo-2',3'-dihydrospiro[cyclohexane-1,1'(2'H)-isoquinoline]; 7-Bromo-1,2,3,4-tetrahydrospiro[isoquinoline-4,1'-cyclohexane]; Spiro[cyclohexane-1,4'-isoquinoline], 7'-bromo-2',3'-dihydro-
EINECS	Contact for details

Quality Control

Our 7'-Bromo-2',3'-dihydro-1'H-spiro[cyclohexane-1,4'-isoquinoline] is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.