Description

3-Amino-n-(4-Methylthiazol-2-Yl)-4-(Trifluoromethyl)-6,7-Dihydro-5H-Cyclopenta[B]Thieno[3,2-E]Pyridine-2-Carboxamide is a sophisticated heterocyclic compound featuring a fused polycyclic structure with a trifluoromethyl group and an amino-thiazole carboxamide moiety. This complex molecular architecture makes it a high-value intermediate for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Chemical Biology Research: Used as a molecular probe or scaffold in studying protein-ligand interactions and biological pathways due to its complex, drug-like structure.
• Medicinal Chemistry: Serves as a core structure for the design and optimization of new chemical entities (NCEs) with potential biological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced synthetic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	3-Amino-n-(4-Methylthiazol-2-Yl)-4-(Trifluoromethyl)-6,7-Dihydro-5H-Cyclopenta[B]Thieno[3,2-E]Pyridine-2-Carboxamide
CAS No.	626222-24-0
Molecular Formula	C18H15F3N4OS2
Molecular Weight	424.46 g/mol
Synonyms	3-Amino-N-(4-methyl-1,3-thiazol-2-yl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide; 3-Amino-N-(4-methylthiazol-2-yl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide; 626222-24-0; CHEMBL3186660; AKOS025147324; ZINC000253909995; DB15490; A1-399/31534052
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.