Description

4-Hydroxy-12-(Trifluoromethyl)-8,9,10,11-Tetrahydro-1H-Cyclohepta[B]Pyrido[2',3':4,5]Thieno[3,2-E]Pyridin-2(7H)-One is a complex, high-value heterocyclic compound featuring a fused polycyclic structure with a trifluoromethyl group, making it a sophisticated building block for advanced chemical synthesis. Its intricate molecular architecture is of significant interest for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for programs targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas where such privileged scaffolds are utilized.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor or scaffold in the synthesis of novel drug candidates, especially in medicinal chemistry research.
• Medicinal Chemistry Research: Used as a key building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions due to its unique heterocyclic structure.
• Advanced Material Synthesis: Potential use in the synthesis of organic electronic materials or specialty polymers where the fused ring system and fluorine content can impart specific properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Hydroxy-12-(Trifluoromethyl)-8,9,10,11-Tetrahydro-1H-Cyclohepta[B]Pyrido[2',3':4,5]Thieno[3,2-E]Pyridin-2(7H)-One
CAS No.	626221-82-7
Molecular Formula	C19H15F3N2O2S
Molecular Weight	392.40 g/mol
Synonyms	4-Hydroxy-12-(trifluoromethyl)-7,8,9,10-tetrahydro-1H-cyclohepta[b]pyrido[2',3':4,5]thieno[3,2-e]pyridin-2(11H)-one; 7,8,9,10-Tetrahydro-4-hydroxy-12-(trifluoromethyl)-1H-cyclohepta[b]pyrido[2',3':4,5]thieno[3,2-e]pyridin-2(11H)-one; CAS 626221-82-7; Fused tricyclic thienopyridinone derivative
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC (for assay and related substances), 1H/13C NMR, IR, and Mass Spectrometry. We support cGMP compliance for materials intended for use in pharmaceutical development and are committed to meeting the specific quality requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.