Description

Ethyl(2E)-4-[(Benzyloxycarbonyl)Amino]But-2-Enoate is a high-purity, protected amino acid derivative widely utilized as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular construction, particularly in the development of novel peptide-based therapeutics and bioactive molecules. Its primary value lies in enabling the controlled introduction of specific functional groups, making it indispensable for pharmaceutical R&D, process chemistry, and fine chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex peptide drugs, protease inhibitors, and other bioactive compounds.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of specific amino acid residues.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Process Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Bioconjugation: Useful in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems.
• Fine Chemical Synthesis: A building block for creating specialized chemicals used in agrochemicals, diagnostics, and material science.

Basic Information

Product Name	Ethyl(2E)-4-[(Benzyloxycarbonyl)Amino]But-2-Enoate
CAS No.	625457-45-6
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	Ethyl (2E)-4-{[(benzyloxy)carbonyl]amino}but-2-enoate; (Z)-Ethyl 4-((((benzyloxy)carbonyl)amino)but-2-enoate; Ethyl 4-(N-Cbz-amino)-2-butenoate; Cbz-4-Amino-crotonic Acid Ethyl Ester; N-Cbz-4-Aminocrotonic Acid Ethyl Ester; (2E)-4-[(Benzyloxycarbonyl)Amino]-2-Butenoic Acid Ethyl Ester; Ethyl trans-4-(Cbz-amino)crotonate; 4-(N-Carbobenzoxyamino)crotonic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl(2E)-4-[(Benzyloxycarbonyl)Amino]But-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.