Description

3-Butyn-1-Amine,4-(2-Pyridinyl)-(9Ci) is a specialized organic building block featuring a pyridine ring and a terminal alkyne functional group, making it a valuable intermediate for advanced synthesis. Its core value lies in enabling the construction of complex molecular architectures through reactions like Sonogashira coupling and click chemistry. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Research: Used in creating new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Ligand Synthesis: Acts as a starting material for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce pyridine and alkyne functionalities into polymer backbones for enhanced material properties.
• Bioconjugation Chemistry: The terminal alkyne group is ideal for bioorthogonal click chemistry reactions used in bioconjugation and probe development.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and target engagement.

Basic Information

Product Name	3-Butyn-1-Amine,4-(2-Pyridinyl)-(9Ci)
CAS No.	625442-20-8
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	4-(Pyridin-2-yl)but-3-yn-1-amine; 4-(2-Pyridyl)-3-butyn-1-amine; 2-(4-Aminobut-1-yn-1-yl)pyridine; 4-(2-Pyridinyl)-3-butyn-1-amine; 3-Butyn-1-amine, 4-(2-pyridinyl)-; 4-(2-Pyridyl)-3-butynylamine; 2-(3-Butynylamino)pyridine (tautomer)
EINECS	Contact for details

Quality Control

Our 3-Butyn-1-Amine,4-(2-Pyridinyl)-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.