Description

3-Amino-6-(3-Methoxyphenyl)-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is a high-value, multifunctional heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring a thienopyridine core with amino, trifluoromethyl, and methoxyphenyl substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and material science for creating compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory research.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging the bioactivity of the thienopyridine scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Biology: Employed as a molecular probe or a core structure in fragment-based drug discovery (FBDD) and high-throughput screening libraries.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies in heterocyclic chemistry and the development of new synthetic routes.

Basic Information

Product Name	3-Amino-6-(3-Methoxyphenyl)-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide
CAS No.	625377-37-9
Molecular Formula	C₁₇H₁₂F₃N₃O₂S
Molecular Weight	379.36 g/mol
Synonyms	3-Amino-6-(3-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-6-(3-methoxyphenyl)-4-(trifluoromethyl)-; 625377-37-9; 3-Amino-6-(3-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid amide; 4-(Trifluoromethyl)-3-amino-6-(3-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of 3-Amino-6-(3-Methoxyphenyl)-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.