Description

3-Amino-6-(3,4-Dimethoxyphenyl)-n-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in medicinal chemistry, enabling the development of targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on creating new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Key intermediate in the research and development of new pharmaceutical compounds.
• Building block for the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Precursor in medicinal chemistry programs exploring thienopyridine-based pharmacophores.
• Used in academic and industrial research for structure-activity relationship (SAR) studies.
• Critical material for process chemistry development and scale-up of candidate drugs.
• Component in the synthesis of potential agrochemicals and other specialty chemicals.

Basic Information

Product Name	3-Amino-6-(3,4-Dimethoxyphenyl)-n-(4-Methoxyphenyl)-4-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide
CAS No.	625369-54-2
Molecular Formula	C24H20F3N3O4S
Molecular Weight	503.50 g/mol
Synonyms	3-Amino-6-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-6-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-4-(trifluoromethyl)-; CAS 625369-54-2; 3-Amino-6-(3,4-dimethoxyphenyl)-N-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxylic acid amide; Advanced Pharmaceutical Intermediate 625369-54-2
EINECS	Contact for details

Quality Control

Our 3-Amino-6-(3,4-Dimethoxyphenyl)-n-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.