Description

8-(Iodomethyl)-1,4-Dioxaspiro[4.5]Decane is a versatile spirocyclic iodomethyl ether, a key synthetic intermediate in advanced organic chemistry. Its value lies in its highly functionalized structure, which provides a reactive iodomethyl handle and a protected ketone equivalent, enabling efficient construction of complex molecular frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of novel active ingredients and complex natural products.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of spirocyclic and bridged-ring compounds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive site for molecular diversification.
• Material Science Research: Serves as a precursor for functional polymers or ligands with specific spirocyclic architectures.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions to introduce complex fragments.
• Natural Product Analog Synthesis: Facilitates the construction of complex terpene-like or polycyclic structures found in natural products.
• Chemical Biology Probe Development: Acts as a starting point for creating molecular probes targeting specific enzymes or biological pathways.

Basic Information

Item	Detail
Product Name	8-(Iodomethyl)-1,4-Dioxaspiro[4.5]Decane
CAS No.	625114-56-9
Molecular Formula	C9H15IO2
Molecular Weight	282.12 g/mol
Synonyms	8-(Iodomethyl)-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane, 8-(iodomethyl)-; 8-Iodomethyl-1,4-dioxaspiro[4.5]decane; Iodomethyl Spiroketal; (1,4-Dioxaspiro[4.5]dec-8-yl)methyl iodide; 8-(Iodomethyl)-1,4-dioxaspiro[4.5]decan; Spiro[1,3-dioxolane-2,1'-cyclohexane], 5'-(iodomethyl)-
EINECS	Contact for details

Quality Control

Our 8-(Iodomethyl)-1,4-Dioxaspiro[4.5]Decane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.