Description

3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require complex nitrogen-containing heterocycles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Advanced Material Research: A building block for organic electronic materials and photoactive compounds due to its fused ring structure.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity brominated naphthyridine derivatives.

Basic Information

Product Name	3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine
CAS No.	625100-00-7
Molecular Formula	C8H9BrN2
Molecular Weight	213.08 g/mol
Synonyms	3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine; 1,6-Naphthyridine, 3-bromo-5,6,7,8-tetrahydro-; 3-Bromotetrahydro-1,6-naphthyridine; 5,6,7,8-Tetrahydro-3-bromo-1,6-naphthyridine; 3-Bromo-1,2,3,4-tetrahydro-1,6-naphthyridine; 3-Bromo-5,6,7,8-tetrahydro[1,6]naphthyridine; 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 625100-00-7)
EINECS	Contact for details

Quality Control

Our 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.