Description

(2S,3R)-Rel-1-Methyl-2-(3-Pyridinyl)-3-Pyrrolidinemethanamine is a high-purity chiral amine building block of significant interest in advanced pharmaceutical synthesis. Its defined stereochemistry and unique heterocyclic structure make it a critical intermediate for developing novel active pharmaceutical ingredients (APIs), particularly in the central nervous system (CNS) and metabolic disorder therapeutic areas. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the development of enantiomerically pure drugs, where precise molecular architecture is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in fine chemical synthesis.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S,3R)-Rel-1-Methyl-2-(3-Pyridinyl)-3-Pyrrolidinemethanamine
CAS No.	623579-03-3
Molecular Formula	C11H17N3
Molecular Weight	191.27 g/mol
Synonyms	1-Methyl-2-(3-pyridinyl)-3-pyrrolidinemethanamine, (2S,3R)-rel-; (2S,3R)-rel-1-Methyl-2-(pyridin-3-yl)-3-(aminomethyl)pyrrolidine; 3-Pyrrolidinemethanamine, 1-methyl-2-(3-pyridinyl)-, (2S,3R)-rel-; (2S,3R)-1-Methyl-2-(3-pyridyl)-3-pyrrolidinylmethylamine; (rel)-(2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinemethanamine
EINECS	Contact for details

Quality Control

Our (2S,3R)-Rel-1-Methyl-2-(3-Pyridinyl)-3-Pyrrolidinemethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.