Description

4-(n-Boc-Amino)-3-Nitropyridine is a high-purity, multi-functional chemical building block designed for advanced organic synthesis. This compound is valued for its dual functionality, featuring a Boc-protected amine group and a nitro substituent on the pyridine ring, which allows for selective transformations and controlled reactivity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the nitropyridine scaffold is required.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and photoactive compounds.
• Academic & R&D Laboratories: A versatile reagent for methodological studies in organic chemistry, including protection/deprotection and cross-coupling reactions.
• Peptide Mimetic Chemistry: The Boc-protected amine is instrumental in constructing peptide-like structures and bio-conjugates.

Basic Information

Product Name	4-(n-Boc-Amino)-3-Nitropyridine
CAS No.	623562-22-1
Molecular Formula	C11H15N3O4
Molecular Weight	253.26 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-3-nitropyridine; 3-Nitro-4-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine; tert-Butyl (3-nitro-4-pyridinyl)carbamate; 4-(Boc-amino)-3-nitropyridine; Boc-4-amino-3-nitropyridine; 4-(tert-Butoxycarbonylamino)-3-nitropyridine; 4-Amino-3-nitropyridine N-Boc derivative
EINECS	Contact for details

Quality Control

Our 4-(n-Boc-Amino)-3-Nitropyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.