Description

5-Isocyanoindol is a versatile and highly reactive heterocyclic building block used in advanced organic synthesis. Its isocyano functional group makes it a critical precursor for constructing complex nitrogen-containing frameworks, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with indole core structures.
• Material Science: Precursor for functional polymers and advanced materials requiring specific indole motifs.
• Chemical Biology & Proteomics: Employed in bioorthogonal chemistry and as a tag for protein labeling and profiling studies.
• Catalyst Ligand Synthesis: Serves as a starting material for creating novel N-heterocyclic carbene (NHC) precursors and other specialized ligands.
• Academic & Contract Research: A valuable reagent for method development and exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	5-Isocyanoindol
CAS No.	623163-58-6
Molecular Formula	C9H6N2
Molecular Weight	142.16 g/mol
Synonyms	5-Isocyano-1H-indole; 1H-Indole-5-carbonitrile; 5-Cyanoindole; 5-Indolecarbonitrile; Indole-5-carbonitrile; 5-Cyano-1H-indole; 5-Isocyanoindole; 5-Indolyl isocyanide
EINECS	Contact for details

Quality Control

Our 5-Isocyanoindol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.