Description

Ethyl 6-(3-Hydroxy-3-Methylbut-1-Ynyl)Nicotinate is a high-value, functionalized nicotinate derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an ester and a hydroxylated alkyne moiety, makes it a versatile intermediate for constructing complex pharmacophores and fine chemicals. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Chemical Research: Serves as a versatile building block for creating complex molecular libraries in combinatorial chemistry and high-throughput screening.
• Material Science: Potential use in the development of organic electronic materials and advanced polymers due to its conjugated system.
• Ligand and Catalyst Development: The functional groups can be utilized to create novel ligands for metal-catalyzed reactions.

Basic Information

Product Name	Ethyl 6-(3-Hydroxy-3-Methylbut-1-Ynyl)Nicotinate
CAS No.	622374-63-4
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	Ethyl 6-(3-hydroxy-3-methylbut-1-yn-1-yl)nicotinate; 3-Pyridinecarboxylic acid, 6-(3-hydroxy-3-methyl-1-butyn-1-yl)-, ethyl ester; 6-(3-Hydroxy-3-methylbut-1-ynyl)nicotinic acid ethyl ester; Ethyl 6-(3-hydroxy-3-methylbut-1-ynyl)pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-(3-Hydroxy-3-Methylbut-1-Ynyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality assurance ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.