Description

n-(5-Bromopyridin-2-Yl)-5-Chloro-1H-Indole-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate with the CAS number 620596-72-7. This compound is a critical building block in modern medicinal chemistry, valued for its precise molecular architecture that enables the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Oncology Drug Development: Serves as a core scaffold for compounds targeting specific cancer pathways.
• CNS-Active Compound Synthesis: Employed in the research and development of agents affecting the central nervous system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.

Basic Information

Product Name	n-(5-Bromopyridin-2-Yl)-5-Chloro-1H-Indole-2-Carboxamide
CAS No.	620596-72-7
Molecular Formula	C14H9BrClN3O
Molecular Weight	350.60 g/mol
Synonyms	5-Chloro-N-(5-bromo-2-pyridinyl)-1H-indole-2-carboxamide; 5-Chloro-1H-indole-2-carboxylic acid (5-bromopyridin-2-yl)amide; 620596-72-7; UNII-8V3Q8Q2R4F; 8V3Q8Q2R4F; BRN 12025853; AKOS005259065; ZINC000003869990
EINECS	Contact for details

Quality Control

Our n-(5-Bromopyridin-2-Yl)-5-Chloro-1H-Indole-2-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.