Description

6-Thien-2-Ylnicotinonitrile 97+%, also known as 3-Cyano-6-thien-2-ylpyridine, is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require sophisticated nitrogen- and sulfur-containing scaffolds, such as medicinal chemistry research and material science, need this high-quality intermediate to drive innovation and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Acts as a precursor for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials due to its conjugated π-system.
• Chemical Synthesis: Employed as a versatile synthon in cross-coupling reactions (e.g., Suzuki, Stille) and cyclization reactions to construct more complex polyheterocyclic systems.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis, including those used in asymmetric synthesis and transition metal catalysis.
• Academic & Industrial R&D: Essential for research laboratories focused on heterocyclic chemistry, medicinal chemistry, and process optimization studies.

Basic Information

Product Name	6-Thien-2-Ylnicotinonitrile 97+% / 3-Cyano-6-Thien-2-Ylpiridine
CAS No.	619334-36-0
Molecular Formula	C10H6N2S
Molecular Weight	186.23 g/mol
Synonyms	3-Cyano-6-(thiophen-2-yl)pyridine; 6-(Thiophen-2-yl)nicotinonitrile; 2-(5-Cyanopyridin-2-yl)thiophene; 3-Cyano-6-(2-thienyl)pyridine; 6-(2-Thienyl)-3-pyridinecarbonitrile; Pyridine, 3-cyano-6-(2-thienyl)-; 619334-36-0; Building Block 619334-36-0
EINECS	Contact for details

Quality Control

Our 6-Thien-2-Ylnicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and meet the specified 97%+ purity grade. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We are committed to supporting cGMP and ISO-guided processes for our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.