Description

1H-Pyrrolo[2,3-B]Pyridine-4-Methanamine, 1-Acetyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 618446-37-0. This compound is a critical building block in modern medicinal chemistry, valued for its unique heterocyclic scaffold that enables the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs and kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Oncology Drug Development: Serves as a core scaffold for compounds targeting specific cancer pathways.
• CNS-Active Compound Synthesis: Employed in creating molecules with potential activity in neurological disorders.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Methanamine, 1-Acetyl- (9Ci)
CAS No.	618446-37-0
Molecular Formula	C10H11N3O
Molecular Weight	189.21 g/mol
Synonyms	1-Acetyl-1H-pyrrolo[2,3-b]pyridine-4-methanamine; 4-(Aminomethyl)-1-acetyl-1H-pyrrolo[2,3-b]pyridine; 1-Acetyl-4-(aminomethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-4-methanamine, 1-acetyl-; 618446-37-0; 1-Acetyl-1H-pyrrolo[2,3-b]pyridin-4-ylmethanamine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Methanamine, 1-Acetyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.