Description

6'-Nitrospiro[Cyclopropane-1,3'-Indoline] is a specialized spirocyclic organic compound featuring a nitro-substituted indoline moiety fused to a cyclopropane ring. This unique molecular architecture makes it a valuable synthetic intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular frameworks, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Investigated for the creation of organic semiconductors, photochromic materials, or non-linear optical (NLO) materials due to its electron-accepting nitro group and rigid spiro structure.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors or receptor ligands for biological studies.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	6'-Nitrospiro[Cyclopropane-1,3'-Indoline]
CAS No.	618446-19-8
Molecular Formula	C11H10N2O2
Molecular Weight	202.21 g/mol
Synonyms	6'-Nitrospiro[cyclopropane-1,3'-indoline]; 6'-Nitro-1'H-spiro[cyclopropane-1,3'-indole]; 6-Nitrospiro(cyclopropane-1,3'-indoline); Spiro[cyclopropane-1,3'-indoline], 6'-nitro-; 618446-19-8; 6'-Nitro-spiro[cyclopropane-1,3'-indoline]; 6-Nitrospiro(cyclopropane-1,3-indoline)
EINECS	Contact for details

Quality Control

Our 6'-Nitrospiro[Cyclopropane-1,3'-Indoline] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.