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(1-(2,4-Difluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazol-4-Yl)Methanol CAS NO 618444-49-8


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CAS No.:618444-49-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1-(2,4-Difluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazol-4-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for the development of new therapeutic and agrochemical agents.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
  • Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with improved efficacy and safety profiles.
  • Agrochemical Development: Serves as a precursor in the research of new fungicides or herbicides, leveraging its difluorophenyl and pyrazole motifs.
  • Biochemical Tool Compound: May be utilized in biochemical assays to study specific biological targets and mechanisms of action.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for clinical trials.

Basic Information

Product Name (1-(2,4-Difluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazol-4-Yl)Methanol
CAS No. 618444-49-8
Molecular Formula C15H11F2N3O
Molecular Weight 287.27 g/mol
Synonyms 4-(Hydroxymethyl)-1-(2,4-difluorophenyl)-3-(3-pyridinyl)-1H-pyrazole; [1-(2,4-Difluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl]methanol; 1-(2,4-Difluorophenyl)-3-(3-pyridyl)-1H-pyrazol-4-ylmethanol; 4-Pyrazolemethanol, 1-(2,4-difluorophenyl)-3-(3-pyridinyl)-; (1-(2,4-Difluorophenyl)-3-(3-pyridinyl)-1H-pyrazol-4-yl)methanol
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Quality Control

Our (1-(2,4-Difluorophenyl)-3-(Pyridin-3-Yl)-1H-Pyrazol-4-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥97.0%
Related Substances (HPLC) Total impurities ≤3.0%
Any single impurity ≤1.0%
Residual Solvents (GC) Complies with ICH Q3C
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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