Description

Ethyl 2-[3-(3-Fluoro-4-Methylbenzoyl)-4-Hydroxy-5-Oxo-2-(3-Pyridinyl)-2,5-Dihydro-1H-Pyrrol-1-Yl]-4-Methyl-1,3-Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially in medicinal chemistry research.
• API Development: Used in the research and process development stages for creating new Active Pharmaceutical Ingredients with potential biological activity.
• Chemical Biology Research: Employed as a probe or scaffold in studying biological pathways and protein interactions due to its unique structural features.
• Process Chemistry Optimization: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value compounds for client-specific projects.

Basic Information

Product Name	Ethyl 2-[3-(3-Fluoro-4-Methylbenzoyl)-4-Hydroxy-5-Oxo-2-(3-Pyridinyl)-2,5-Dihydro-1H-Pyrrol-1-Yl]-4-Methyl-1,3-Thiazole-5-Carboxylate
CAS No.	618072-71-2
Molecular Formula	C25H22FN3O5S
Molecular Weight	495.52 g/mol
Synonyms	Ethyl 4-methyl-2-[3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-2-(pyridin-3-yl)-2,5-dihydro-1H-pyrrol-1-yl]-1,3-thiazole-5-carboxylate; 1,3-Thiazole-5-carboxylic acid, 2-[3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-2-(3-pyridinyl)-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-, ethyl ester; CAS 618072-71-2; Pyrrole-thiazole carboxylate derivative; Fluoromethylbenzoyl pyrrolothiazole ester.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development work with material produced under GMP-like conditions where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.