Description

4-Oxazolecarboxylicacid,2-Ethynyl-,Ethylester(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the ethynyl and ester functional groups attached to the oxazole ring, enabling the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Building Block: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study biological pathways and protein interactions.
• Cross-Coupling Reactions: The ethynyl group makes it a valuable substrate for Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Chemistry Research: Fundamental research into the synthesis and reactivity of functionalized oxazole derivatives.

Basic Information

Product Name	4-Oxazolecarboxylicacid,2-Ethynyl-,Ethylester(9Ci)
CAS No.	617705-26-7
Molecular Formula	C8H7NO3
Molecular Weight	165.15 g/mol
Synonyms	2-Ethynyl-1,3-oxazole-4-carboxylic acid ethyl ester; Ethyl 2-ethynyloxazole-4-carboxylate; 2-Ethynyl-4-oxazolecarboxylic Acid Ethyl Ester; 4-Carbethoxy-2-ethynyloxazole; 2-Ethynyloxazole-4-carboxylic acid ethyl ester; Ethyl 2-ethynyl-1,3-oxazole-4-carboxylate; 617705-26-7; 2-Ethynyl-4-(ethoxycarbonyl)oxazole
EINECS	Contact for details

Quality Control

Our 4-Oxazolecarboxylicacid,2-Ethynyl-,Ethylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.