Description

5-(Trifluoromethyl)-1H-Imidazo[4,5-B]Pyridine is a high-value, heterocyclic organic compound featuring a fused imidazopyridine core substituted with a trifluoromethyl group. This structure is critical for its role as a versatile and potent building block in modern pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients. The compound's unique electronic properties, imparted by the fluorine atoms, make it instrumental in modulating the bioavailability, metabolic stability, and binding affinity of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small-molecule drugs, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the design and synthesis of new generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced lipophilicity and biological activity.
• Material Science Precursor: Serves as a specialized ligand or functional group in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the creation of molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Imidazo[4,5-B]Pyridine
CAS No.	617678-32-7
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	1H-Imidazo[4,5-b]pyridine, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)imidazo[4,5-b]pyridine; 5-Trifluoromethyl-1H-imidazo[4,5-b]pyridine; 617678-32-7; AI3-63185; AKOS040751830; BCP32413; CS-W009767; FT-0773299; NSC 405124; SCHEMBL15542519
EINECS	Contact for details

Quality Control

We supply 5-(Trifluoromethyl)-1H-Imidazo[4,5-B]Pyridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.