Description

4-Bromo-2-Methyl-6-(Trifluoromethyl)Pyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents, makes it an exceptionally valuable intermediate for introducing specific functional groups into target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of molecular probes and tags.
• Custom Synthesis and Scale-up: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	4-Bromo-2-Methyl-6-(Trifluoromethyl)Pyridine
CAS No.	615580-45-5
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	4-Bromo-2-methyl-6-(trifluoromethyl)pyridine; 2-Methyl-4-bromo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-4-bromo-2-picoline; 4-Bromo-2-methyl-6-trifluoromethylpyridine; 2-Methyl-4-bromo-6-trifluoromethylpyridine; 4-Bromo-2-methyl-6-(trifluoromethyl)pyridine (CAS 615580-45-5)
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Methyl-6-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.