Description

6-(Hydroxymethyl)-2H-Pyrido[3,2-B][1,4]Oxazin-3(4H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in research and development for constructing sophisticated heterocyclic frameworks due to its reactive hydroxymethyl and oxazinone functional groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in the discovery of new pharmacologically active compounds.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	6-(Hydroxymethyl)-2H-Pyrido[3,2-B][1,4]Oxazin-3(4H)-One
CAS No.	615568-38-2
Molecular Formula	C8H8N2O3
Molecular Weight	180.16 g/mol
Synonyms	6-(Hydroxymethyl)-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-3-one; 6-(Hydroxymethyl)-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one; 6-Hydroxymethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one; Pyrido[3,2-b][1,4]oxazin-3(4H)-one, 6-(hydroxymethyl)-; 615568-38-2; 6-Hydroxymethyl-pyrido[3,2-b]oxazin-3-one
EINECS	Contact for details

Quality Control

Our 6-(Hydroxymethyl)-2H-Pyrido[3,2-B][1,4]Oxazin-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.