Description

6-Iodo-[1,2,4]Triazolo[1,5,A]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique triazolopyridine scaffold offers versatile reactivity. It is primarily needed by research scientists and process chemists in pharmaceutical R&D, agrochemical discovery, and material science laboratories for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the iodinated triazolopyridine core.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, organic semiconductors, and photoactive compounds for electronic applications.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to introduce the triazolopyridine moiety into more complex systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	6-Iodo-[1,2,4]Triazolo[1,5,A]Pyridine
CAS No.	614750-84-4
Molecular Formula	C6H3IN4
Molecular Weight	257.01 g/mol
Synonyms	6-Iodo-[1,2,4]triazolo[1,5-a]pyridine; 6-Iodo-1,2,4-triazolo[1,5-a]pyridine; [1,2,4]Triazolo[1,5-a]pyridine, 6-iodo-; 6-Iodotriazolopyridine; 6-Iodo-1,2,4-triazolopyridine; 6-Iodo-s-triazolo[1,5-a]pyridine; 6-Iodo-1,2,4-triazolo[1,5-a]pyridine (CAS 614750-84-4)
EINECS	Contact for details

Quality Control

Our 6-Iodo-[1,2,4]Triazolo[1,5,A]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and agrochemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.