Description

5-Chloro-2-Oxo-1,2-Dihydro-3-Pyridinecarbaldehyde is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an aldehyde group and a halogenated pyridone structure, enabling its use in constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, including kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and CDMOs requiring reliable, high-quality building blocks for client projects.

Basic Information

Product Name	5-Chloro-2-Oxo-1,2-Dihydro-3-Pyridinecarbaldehyde
CAS No.	614732-03-5
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	5-Chloro-2-oxo-1,2-dihydropyridine-3-carbaldehyde; 3-Formyl-5-chloro-2(1H)-pyridinone; 5-Chloro-3-formyl-2(1H)-pyridone; 5-Chloro-2-hydroxynicotinaldehyde; 5-Chloro-1,2-dihydro-2-oxo-3-pyridinecarboxaldehyde; 5-Chloro-2-pyridone-3-carboxaldehyde; 3-Aldehyde-5-chloro-2-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Oxo-1,2-Dihydro-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and other high-value chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.