Description

4-[[2-(Trifluoromethyl)Phenoxy]Methyl]-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 614731-26-9. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and commercial-scale production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, especially in neurological and psychiatric drug development.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures containing piperidine and trifluoromethylphenoxy motifs.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial research for pharmacological studies and new chemical entity (NCE) development.
• Agrochemical Intermediate: Potential application in the synthesis of advanced crop protection agents and pesticides.
• Material Science: Can be utilized in the development of specialty polymers and functional materials.

Basic Information

Product Name	4-[[2-(Trifluoromethyl)Phenoxy]Methyl]-Piperidine Hydrochloride
CAS No.	614731-26-9
Molecular Formula	C14H18F3NO·HCl
Molecular Weight	309.76 g/mol (Free base: 273.30 g/mol)
Synonyms	4-[(2-Trifluoromethylphenoxy)methyl]piperidine hydrochloride; 4-((2-(Trifluoromethyl)phenoxy)methyl)piperidine HCl; 1-[(2-Trifluoromethylphenoxy)methyl]-4-piperidine hydrochloride; Piperidine, 4-[[2-(trifluoromethyl)phenoxy]methyl]-, hydrochloride (1:1); CAS 614731-26-9
EINECS	Contact for details

Quality Control

Our 4-[[2-(Trifluoromethyl)Phenoxy]Methyl]-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.