Description

1-Boc-4-Fluoro-4-Formyl-Piperidine is a high-purity, multifunctional piperidine derivative, serving as a critical building block in modern organic synthesis. Its value lies in the strategic combination of a protected amine (Boc), a fluorine substituent, and an aldehyde functional group, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and complex chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used to construct novel herbicide and pesticide molecules, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Peptidomimetics & PROTACs: Serves as a versatile scaffold for designing peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) in drug discovery.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and specialty chemicals.
• Chemical Biology Probes: Utilized to synthesize labeled compounds and molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	1-Boc-4-Fluoro-4-Formyl-Piperidine
CAS No.	614731-09-8
Molecular Formula	C11H18FNO3
Molecular Weight	231.27 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-fluoro-4-formylpiperidine; 4-Fluoro-4-formylpiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-fluoro-4-formylpiperidine-1-carboxylate; N-Boc-4-fluoro-4-formylpiperidine; 1-Boc-4-fluoro-4-piperidinecarboxaldehyde; 4-Formyl-4-fluoro-1-piperidinecarboxylic acid tert-butyl ester; Boc-4-fluoro-4-formylpiperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Fluoro-4-Formyl-Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.