Description

1,2-Cyclopropanedicarboxylicacid,3-Methyl-,Monomethylester,(1S,2R,3R)-(9Ci) is a high-purity, stereochemically defined cyclopropane derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with precise three-dimensional architecture. It is essential for research and development in the pharmaceutical, agrochemical, and specialty chemical industries, where its defined stereochemistry is crucial for biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological efficacy and stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in enantioselective synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific stereochemical properties.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in methodology development and the construction of complex natural product analogs.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value specialty chemicals for various technological applications.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid,3-Methyl-,Monomethylester,(1S,2R,3R)-(9Ci)
CAS No.	613681-19-9
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(1S,2R,3R)-3-Methylcyclopropane-1,2-dicarboxylic acid monomethyl ester; (1S,2R,3R)-Methyl 3-methylcyclopropane-1,2-dicarboxylate; 3-Methylcyclopropane-1,2-dicarboxylic acid monomethyl ester, (1S,2R,3R)-; Monomethyl (1S,2R,3R)-3-methylcyclopropane-1,2-dicarboxylate; (1S,2R,3R)-3-Methyl-1,2-cyclopropanedicarboxylic acid monomethyl ester
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclopropanedicarboxylicacid,3-Methyl-,Monomethylester,(1S,2R,3R)-(9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with customer specifications and high industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,2R,3R)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.