Description

(3-Bromo-5-Methoxy-4-Pyridinyl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex pyridine-based heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated pyridine motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and bio-conjugates for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Item	Details
Product Name	(3-Bromo-5-Methoxy-4-Pyridinyl)Boronic Acid
CAS No.	612845-45-1
Molecular Formula	C6H7BBrNO3
Molecular Weight	231.84 g/mol
Synonyms	4-Pyridineboronic acid, 3-bromo-5-methoxy-; (3-Bromo-5-methoxypyridin-4-yl)boronic acid; 3-Bromo-5-methoxy-4-pyridineboronic acid; 4-Borono-3-bromo-5-methoxypyridine; 3-Bromo-5-methoxy-4-pyridylboronic acid; Boronic acid, B-(3-bromo-5-methoxy-4-pyridinyl)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (3-Bromo-5-Methoxy-4-Pyridinyl)Boronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.