Description

Ethyl 5-Iodo-2-Methylbenzoate is a high-purity, halogenated aromatic ester building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of iodine and methyl groups, which enable selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials through cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores for further derivatization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its reactive iodine site.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and liquid crystals with unique electronic properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings to form new carbon-carbon bonds.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal chemistry and drug discovery programs targeting various disease pathways.

Basic Information

Product Name	Ethyl 5-Iodo-2-Methylbenzoate
CAS No.	612833-45-1
Molecular Formula	C10H11IO2
Molecular Weight	290.10 g/mol
Synonyms	5-Iodo-2-methylbenzoic Acid Ethyl Ester; Ethyl 5-Iodo-o-toluate; Benzoic acid, 5-iodo-2-methyl-, ethyl ester; 2-Methyl-5-iodobenzoic Acid Ethyl Ester; o-Toluic acid, 5-iodo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Iodo-2-Methylbenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.