Description

1-(sec-Butylamino)-3-Isopropylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers and R&D laboratories engaged in developing new therapeutic agents, especially within oncology and antiviral drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds in drug discovery programs.
• API Synthesis: Serves as a precursor in the production of complex active pharmaceutical ingredients (APIs) with benzo[4,5]imidazo[1,2-a]pyridine core structures.
• Chemical Biology Probes: Utilized in the development of specialized molecular probes for studying biological processes and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.
• Academic Research: Employed in university and institutional labs for advanced studies in heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	1-(sec-Butylamino)-3-Isopropylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile
CAS No.	612523-49-6
Molecular Formula	C19H22N4
Molecular Weight	306.41 g/mol
Synonyms	1-[(2-Butyl)amino]-3-(1-methylethyl)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; 3-Isopropyl-1-(sec-butylamino)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; Benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile, 1-[(1-methylpropyl)amino]-3-(1-methylethyl)-; 1-(sec-Butylamino)-3-isopropyl-1H-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; 612523-49-6; BIP-CN Intermediate
EINECS	Contact for details

Quality Control

Our 1-(sec-Butylamino)-3-Isopropylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.