Description

Trans 1-Benzyl-4-(4-Fluorophenyl)-6-Oxopiperidine-3-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and neurological research areas. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for process development and scale-up activities.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block in the multi-step synthesis of novel pharmaceutical compounds.
• Neurological & CNS Drug Research: Used in the development of potential therapeutics targeting specific neurological pathways and receptors.
• Medicinal Chemistry & Lead Optimization: Provides a versatile scaffold for structural modification and activity studies in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable manufacturing routes for target molecules.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Trans 1-Benzyl-4-(4-Fluorophenyl)-6-Oxopiperidine-3-Carboxylic Acid Methyl Ester
CAS No.	612095-72-4
Molecular Formula	C20H20FNO3
Molecular Weight	341.38 g/mol
Synonyms	Methyl (3R,4S)-1-Benzyl-4-(4-fluorophenyl)-6-oxopiperidine-3-carboxylate; (3R,4S)-1-Benzyl-4-(4-fluorophenyl)-6-oxopiperidine-3-carboxylic acid methyl ester; 1-Benzyl-4-(4-fluorophenyl)-6-oxopiperidine-3-carboxylic acid methyl ester, trans-; trans-1-Benzyl-4-(4-fluorophenyl)-6-oxo-3-piperidinecarboxylic acid methyl ester; 612095-72-4; Methyl 1-benzyl-4-(4-fluorophenyl)-6-oxopiperidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Trans 1-Benzyl-4-(4-Fluorophenyl)-6-Oxopiperidine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via NMR and MS. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.