Description

6-(Pyridin-2-Ylamino)-2,3-Dihydro-1H-Indolizin-5-One is a high-purity, advanced pharmaceutical intermediate and research chemical with the CAS number 612065-10-8. This compound is valued for its unique heterocyclic structure, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic & Institutional Research: Utilized in universities and research institutes for investigating new organic reactions and catalytic processes.

Basic Information

Product Name	6-(Pyridin-2-Ylamino)-2,3-Dihydro-1H-Indolizin-5-One
CAS No.	612065-10-8
Molecular Formula	C₁₇H₁₆N₄O
Molecular Weight	292.34 g/mol
Synonyms	6-[(Pyridin-2-yl)amino]-2,3-dihydro-1H-indolizin-5-one; 6-(2-Pyridinylamino)-2,3-dihydro-1H-indolizin-5-one; 612065-10-8; 5H-Indolizin-5-one, 6-[(2-pyridinyl)amino]-2,3-dihydro-; 6-(Pyridin-2-ylamino)-2,3-dihydro-1H-indolizin-5-one; 6-(2-Pyridylamino)-2,3-dihydro-1H-indolizin-5-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.