Description

4-(2-Methylimidazo[1,2-A]Pyridin-3-Yl)-2-Pyrimidinamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Biochemical Reagent: Serves as a reference standard or reagent in biochemical assays and pharmacological studies.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex heterocyclic compounds and specialized fine chemicals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for chemical methodology development and bioorganic research.

Basic Information

Product Name	4-(2-Methylimidazo[1,2-A]Pyridin-3-Yl)-2-Pyrimidinamine
CAS No.	611239-37-3
Molecular Formula	C12H11N5
Molecular Weight	225.25 g/mol
Synonyms	2-Pyrimidinamine, 4-(2-methylimidazo[1,2-a]pyridin-3-yl)-; 4-(2-Methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-amine; 4-(2-Methylimidazo[1,2-A]Pyridin-3-Yl)-2-Aminopyrimidine; 2-Amino-4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidine; GDC-0941 Impurity; Pictilisib Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-(2-Methylimidazo[1,2-A]Pyridin-3-Yl)-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The material is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.