Description

5-Phenyl-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, heterocyclic organic compound featuring a fused pyrrolopyridine core with a phenyl substituent. This specific molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel active ingredients. The compound's structure is integral to developing targeted therapies, particularly in oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities (NCEs).
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent, selective kinase inhibitors for cancer treatment.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Organic Light-Emitting Diode (OLED) Materials: Potential application as an electron-transporting or host material in the development of advanced optoelectronic devices.
• Agrochemical Synthesis: Intermediate in the research and development of new-generation herbicides or fungicides with specific modes of action.
• Academic & Industrial Research: Used in chemical research to study heterocyclic chemistry, photophysical properties, and novel reaction pathways.

Basic Information

Product Name	5-Phenyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	611205-38-0
Molecular Formula	C15H12N2
Molecular Weight	220.27 g/mol
Synonyms	5-Phenyl-1H-pyrrolo[2,3-b]pyridine; 5-Phenyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-phenyl-; 5-Phenyl-7-azaindole; 5-Phenyl-1H-7-azaindole; 5-Phenyl-pyrrolo[2,3-b]pyridine; 5-Phenyl-1H-pyrrolo[2,3-b]pyridine (9CI)
EINECS	Contact for details

Quality Control

Our 5-Phenyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.