Description

5-(3-Fluorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the synthesis of small molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the research and development of new drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Employed in the construction of complex fused-ring systems and fluorinated heterocycles for advanced material science applications.
• Biochemical Research: May be utilized as a tool compound or precursor in biochemical assays and proteomics research.
• Agrochemical Development: Acts as a potential intermediate in the synthesis of novel agrochemicals and plant protection agents.

Basic Information

Product Name	5-(3-Fluorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One
CAS No.	611204-90-1
Molecular Formula	C13H9FN2O
Molecular Weight	228.22 g/mol
Synonyms	5-(3-Fluorophenyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; 5-(3-Fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 2H-Pyrrolo[2,3-b]pyridin-2-one, 5-(3-fluorophenyl)-1,3-dihydro-; 5-(3-Fluorophenyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 5-(3-Fluorophenyl)-3H-pyrrolo[2,3-b]pyridin-2-one; Fluorinated pyrrolopyridinone; 3-Fluorophenyl pyrrolopyridinone derivative
EINECS	Contact for details

Quality Control

Our 5-(3-Fluorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.