Description

D-Alloisoleucine, n-Methyl-, Methyl Ester (9Ci) is a specialized, non-proteinogenic amino acid derivative with a defined stereochemistry. This compound is of significant value as a high-purity chiral building block and intermediate in advanced organic synthesis. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and other bioactive molecules where precise stereochemical control is critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, including peptide-based drugs and enzyme inhibitors.
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis to introduce modified isoleucine residues, studying structure-activity relationships.
• Biochemical Research: Employed as a standard or probe in metabolic studies and enzymatic assays to investigate amino acid metabolism and transport.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in the synthesis of complex natural products and other enantiomerically pure compounds.
• Protecting Group Strategy: The methyl ester functionality provides a handle for further chemical modification and deprotection sequences in multi-step syntheses.

Basic Information

Item	Details
Product Name	D-Alloisoleucine, n-Methyl-, Methyl Ester (9Ci)
CAS No.	610800-54-9
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	Methyl (2R,3S)-2-(Methylamino)-3-methylpentanoate; D-α-Alloisoleucine N-Methyl Methyl Ester; Methyl N-Methyl-D-α-alloisoleucinate; (2R,3S)-2-(Methylamino)-3-methylpentanoic Acid Methyl Ester; D-N-Methylalloisoleucine Methyl Ester; (R,S)-N-Methylisoleucine Methyl Ester (specific to D-allo form); D-2-Amino-3-methyl-N-methylpentanoic Acid Methyl Ester (alloisoleucine isomer)
EINECS	Contact for details

Quality Control

Our production of D-Alloisoleucine, n-Methyl-, Methyl Ester (9Ci) adheres to stringent in-house quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by modern analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% de (D-allo isomer)
Optical Rotation	Specific rotation provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.