Description

2-Piperidinecarboxylicacid,1,4-Dimethyl-,(2R,4S)-Rel-(9Ci) is a high-purity chiral piperidine derivative, a crucial building block in advanced organic synthesis. Its defined stereochemistry at the 2 and 4 positions makes it an invaluable intermediate for the development of novel pharmaceuticals and bioactive compounds. This product is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is required for efficacy and selectivity. CAS number 610786-78-2.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its piperidine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and other specialty chemicals.
• Biochemical Research: Utilized as a reference standard or building block in medicinal chemistry and drug discovery programs.

Basic Information

Item	Detail
Product Name	2-Piperidinecarboxylicacid,1,4-Dimethyl-,(2R,4S)-Rel-(9Ci)
CAS No.	610786-78-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(2R,4S)-1,4-Dimethylpipecolic Acid; (2R,4S)-1,4-Dimethyl-2-piperidinecarboxylic Acid; (2R,4S)-1,4-Dimethylpiperidine-2-carboxylic Acid; Rel-(2R,4S)-1,4-Dimethyl-2-piperidinecarboxylic Acid; 1,4-Dimethyl-DL-pipecolic Acid (stereoisomer); 1,4-Dimethylpipecolic Acid (Relative configuration); (2R,4S)-1,4-Dimethylpipecolate
EINECS	Contact for details

Quality Control

Every batch of 2-Piperidinecarboxylicacid,1,4-Dimethyl-,(2R,4S)-Rel-(9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available for each lot. Our quality protocols are designed to support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.