Description

Ethyl 1-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-carboxylate structure. This compound is of significant commercial value for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the trifluoromethyl and nitro functional groups for enhanced bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	Ethyl 1-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperidine-4-Carboxylate
CAS No.	610259-53-5
Molecular Formula	C15H17F3N2O4
Molecular Weight	346.30 g/mol
Synonyms	Ethyl 1-(2-Nitro-4-(trifluoromethyl)phenyl)piperidine-4-carboxylate; 1-[2-Nitro-4-(trifluoromethyl)phenyl]-4-piperidinecarboxylic Acid Ethyl Ester; 4-Carbethoxy-1-(2-nitro-4-trifluoromethylphenyl)piperidine; Piperidine-4-carboxylic acid, 1-[2-nitro-4-(trifluoromethyl)phenyl]-, ethyl ester; Ethyl 4-piperidinecarboxylate, 1-(2-nitro-4-trifluoromethylphenyl) derivative
EINECS	Contact for details

Quality Control

Our Ethyl 1-[2-Nitro-4-(Trifluoromethyl)Phenyl]Piperidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.