Description

2-Propen-1-Ol,3-[(2R)-2-Methyl-1,4-Dioxaspiro[4.4]Non-2-Yl]-,(2E)-(9Ci) is a specialized chiral building block featuring a spiroacetal-protected diol moiety and an allylic alcohol group. This compound matters as a high-value intermediate for the stereoselective synthesis of complex natural products and pharmaceuticals, offering precise control over molecular architecture. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of bioactive molecules, including macrolide antibiotics and polyketide-derived therapeutics.
• Agrochemical Research: Used in developing novel, stereochemically defined active ingredients for crop protection.
• Fine Chemical Synthesis: Serves as a versatile precursor for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Process Chemistry: Employed in methodological studies for new asymmetric synthesis routes and scale-up process development.
• Material Science: Potential monomer for creating polymers with unique chiral or functional properties.

Basic Information

Product Name	2-Propen-1-Ol,3-[(2R)-2-Methyl-1,4-Dioxaspiro[4.4]Non-2-Yl]-,(2E)-(9Ci)
CAS No.	609842-67-3
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	(2E)-3-[(2R)-2-Methyl-1,4-dioxaspiro[4.4]non-2-yl]prop-2-en-1-ol; (E)-3-((R)-2-Methyl-1,4-dioxaspiro[4.4]nonan-2-yl)allyl Alcohol; 2-Propen-1-ol, 3-[(2R)-2-methyl-1,4-dioxaspiro[4.4]non-2-yl]-, (2E)-; Chiral Spiroacetal Allylic Alcohol; (R,E)-Spiroacetal Allyl Alcohol Intermediate
EINECS	Contact for details

Quality Control

Our 2-Propen-1-Ol,3-[(2R)-2-Methyl-1,4-Dioxaspiro[4.4]Non-2-Yl]-,(2E)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.