Description

Propanedioic Acid, 2-(Acetylamino)-2-(1-Methylethyl)-, 1-Ethyl Ester is a specialized malonic acid derivative featuring an acetylamino and isopropyl substituent, offering a unique sterically hindered structure for advanced synthetic applications. This compound is valued for its role as a versatile chiral building block and intermediate in the synthesis of complex organic molecules, where precise molecular architecture is critical. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered amino acid analogs.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and plant growth regulators with tailored biological activity.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including complex ligands for catalysis, dyes, and advanced polymeric materials.
• Academic & Industrial Research: A valuable reagent in organic synthesis for methodological studies, asymmetric synthesis, and the development of new chemical entities.
• Peptidomimetics & Bioactive Molecule Design: Its structure makes it suitable for constructing peptidomimetics and other bioactive compounds that mimic natural peptides.

Basic Information

Product Name	Propanedioic Acid, 2-(Acetylamino)-2-(1-Methylethyl)-, 1-Ethyl Ester
CAS No.	609346-34-1
Molecular Formula	C10H17NO5
Molecular Weight	231.25 g/mol
Synonyms	1-Ethyl 2-(acetylamino)-2-isopropylmalonate; Ethyl 2-Acetamido-2-isopropylmalonate; 2-(Acetylamino)-2-isopropylmalonic Acid Ethyl Ester; 2-Acetamido-2-isopropylmalonic Acid Ethyl Ester; AIMM Ethyl Ester; N-Acetyl-α-isopropylmalonic Acid Ethyl Ester; Ethyl N-Acetyl-α-isopropylmalonate; Ethyl 2-(Acetylamino)-2-(1-methylethyl)propanedioate
EINECS	Contact for details

Quality Control

Our Propanedioic Acid, 2-(Acetylamino)-2-(1-Methylethyl)-, 1-Ethyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.