Description

Pactimibe Sulfate CAS NO 608510-47-0 is the sulfate salt form of Pactimibe, a compound known for its role as an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of cardiovascular and metabolic diseases. It is primarily utilized by research institutions, pharmaceutical manufacturers, and CROs (Contract Research Organizations) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced drug candidates targeting cholesterol metabolism.
• Biochemical Research: Used in in vitro and in vivo studies to investigate the mechanisms of ACAT inhibition and lipid regulation.
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Preclinical Development: Integral to the discovery and early-stage development pipeline for potential therapeutics aimed at atherosclerosis and related disorders.

Basic Information

Product Name	Pactimibe Sulfate
CAS No.	608510-47-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pactimibe Sulphate; CS-505 Sulfate; N-[[2,6-Bis(1-methylethyl)phenyl]thio]-2-oxo-1-[[2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-3-pyrrolidineacetamide Sulfate; Pactimibe Sulphate Salt; Pactimibe Hydrogen Sulfate
EINECS	Contact for details

Quality Control

Our Pactimibe Sulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.