Description

tert-Butyl 4-(3-Nitropyridin-4-yl)piperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with a nitropyridine substituent. This compound is valued for its role as a critical building block in the synthesis of complex, nitrogen-containing heterocycles, particularly for active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including kinase inhibitors and other small molecule drugs. The product is supplied with full analytical documentation to support rigorous R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted drug candidates, especially in oncology and CNS research.
• Kinase Inhibitor Development: Serves as a core scaffold for constructing molecules designed to modulate kinase activity.
• Chemical Research & Development: Used in academic and industrial labs for exploring new synthetic routes to complex heterocyclic systems.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for producing bespoke compounds for client projects.
• Process Chemistry: Integral in route scouting and optimization studies for the commercial-scale production of APIs.

Basic Information

Product Name	tert-Butyl 4-(3-Nitropyridin-4-yl)piperazine-1-carboxylate
CAS No.	608142-93-4
Molecular Formula	C14H20N4O4
Molecular Weight	308.33 g/mol
Synonyms	1-Boc-4-(3-Nitro-4-pyridyl)piperazine; tert-Butyl 4-(3-nitro-4-pyridinyl)-1-piperazinecarboxylate; 4-(3-Nitropyridin-4-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-nitropyridin-4-yl)piperazine; Boc-4-(3-nitro-4-pyridyl)piperazine; 608142-93-4; 4-Piperazinecarboxylic acid, 4-(3-nitro-4-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-(3-Nitropyridin-4-yl)piperazine-1-carboxylate is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.