Description

Butanoic Acid, 2-Amino-4,4-Difluoro-, Methyl Ester, (2S)- (9Ci) is a high-purity, chiral fluorinated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the precise introduction of fluorine atoms and a protected amino acid backbone, which are essential for modulating the biological activity and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetics Synthesis: Used in the construction of fluorinated peptide analogs to enhance their stability, bioavailability, and binding affinity.
• Agrochemical Research: Serves as a building block for developing new generations of fluorinated herbicides, insecticides, and fungicides with improved efficacy.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Potential precursor for specialty polymers and advanced materials where fluorine incorporation can alter surface properties and stability.

Basic Information

Product Name	Butanoic Acid, 2-Amino-4,4-Difluoro-, Methyl Ester, (2S)- (9Ci)
CAS No.	607403-55-4
Molecular Formula	C5H9F2NO2
Molecular Weight	153.13 g/mol
Synonyms	(S)-Methyl 2-amino-4,4-difluorobutanoate; L-2-Amino-4,4-difluorobutanoic acid methyl ester; (2S)-2-Amino-4,4-difluorobutanoic acid methyl ester; Methyl (2S)-2-amino-4,4-difluorobutanoate; 4,4-Difluoro-L-homoalanine methyl ester; 2-Amino-4,4-difluorobutyric acid methyl ester, (S)-
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 2-Amino-4,4-Difluoro-, Methyl Ester, (2S)- (9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques, including chiral HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged storage or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.