Description

1H-Pyrrolo[3,2-C]Pyridine, 5-Acetyl-1-Ethenyl-4,5,6,7-Tetrahydro- (9Ci) is a high-purity, advanced pharmaceutical intermediate (API intermediate) with the CAS number 606967-18-4. This heterocyclic compound is valued for its complex fused-ring structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the areas of kinase inhibitors and central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Kinase Inhibitor Development: Its pyrrolopyridine core is integral to designing potent and selective kinase inhibitors for oncology applications.
• CNS Drug Discovery: Used in the synthesis of compounds targeting neurological disorders due to its ability to cross the blood-brain barrier.
• Chemical Synthesis: Employed in organic synthesis for constructing complex nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1H-Pyrrolo[3,2-C]Pyridine, 5-Acetyl-1-Ethenyl-4,5,6,7-Tetrahydro- (9Ci)
CAS No.	606967-18-4
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	5-Acetyl-1-ethenyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine; 1-Vinyl-5-acetyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine; 4,5,6,7-Tetrahydro-5-acetyl-1-vinyl-1H-pyrrolo[3,2-c]pyridine; 606967-18-4; 1H-Pyrrolo[3,2-c]pyridine, 5-acetyl-1-ethenyl-4,5,6,7-tetrahydro-; 5-Acetyl-1-vinyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-C]Pyridine, 5-Acetyl-1-Ethenyl-4,5,6,7-Tetrahydro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.