Description

5-Pyrimidinecarbonitrile,2-(2-Furanyl)-1,4-Dihydro-6-Methyl-4,4-Bis(Trifluoromethyl)-(9Ci) is a high-value, fluorinated pyrimidine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex molecular architecture, featuring both a pyrimidine core and trifluoromethyl groups, makes it indispensable for constructing novel compounds with tailored properties. This specialty chemical is primarily sought by research institutions and pharmaceutical companies engaged in the development of new agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and antiviral therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for creating specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure and fluorine content.
• Chemical Synthesis: Acts as a versatile scaffold in medicinal and combinatorial chemistry for constructing diverse heterocyclic libraries for high-throughput screening.
• Fluorine Chemistry Studies: Employed in academic and industrial R&D to study the effects of polyfluorinated alkyl groups on molecular conformation and reactivity.

Basic Information

Product Name	5-Pyrimidinecarbonitrile,2-(2-Furanyl)-1,4-Dihydro-6-Methyl-4,4-Bis(Trifluoromethyl)-(9Ci)
CAS No.	606924-12-3
Molecular Formula	C13H7F6N3O
Molecular Weight	335.21 g/mol
Synonyms	2-(Furan-2-yl)-1,4-dihydro-6-methyl-4,4-bis(trifluoromethyl)pyrimidine-5-carbonitrile; 2-(2-Furanyl)-1,4-dihydro-6-methyl-4,4-bis(trifluoromethyl)-5-pyrimidinecarbonitrile; 4,4-Bis(trifluoromethyl)-2-(2-furyl)-1,4-dihydro-6-methyl-5-pyrimidinecarbonitrile; 606924-12-3; AI3-52310; CTK8G0332; NSC 796855; ZINC000103014577
EINECS	Contact for details

Quality Control

Our production of 5-Pyrimidinecarbonitrile,2-(2-Furanyl)-1,4-Dihydro-6-Methyl-4,4-Bis(Trifluoromethyl)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.