Description

4H-1,4-Benzoxazine-4-Acetamide,n-[(2-Chloro-6-Fluorophenyl)Methyl]-2-Ethyl-2,3-Dihydro-6-Methyl-3-Oxo-n-(3-Pyridinylmethyl)-(9Ci) is a high-purity, complex heterocyclic organic compound serving as a critical advanced intermediate in pharmaceutical research and development. Its intricate molecular structure, featuring benzoxazine, pyridine, and fluorinated phenyl motifs, makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it enables the exploration of new therapeutic pathways and the optimization of synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Chemical Biology Probe: Serves as a scaffold or precursor in the design of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial production of complex molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Used in university and institutional laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4H-1,4-Benzoxazine-4-Acetamide,n-[(2-Chloro-6-Fluorophenyl)Methyl]-2-Ethyl-2,3-Dihydro-6-Methyl-3-Oxo-n-(3-Pyridinylmethyl)-(9Ci)
CAS No.	606120-43-8
Molecular Formula	C26H25ClFN3O3
Molecular Weight	481.95 g/mol
Synonyms	N-[(2-Chloro-6-fluorophenyl)methyl]-2-ethyl-2,3-dihydro-6-methyl-3-oxo-N-(pyridin-3-ylmethyl)-4H-1,4-benzoxazine-4-acetamide; 4H-1,4-Benzoxazine-4-acetamide, N-[(2-chloro-6-fluorophenyl)methyl]-2-ethyl-2,3-dihydro-6-methyl-3-oxo-N-(3-pyridinylmethyl)-; 606120-43-8; UNII-9I0C8QY8QN; 9CI; SCHEMBL2180621; AKOS040757623; DB14960
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under a strict quality management system. Standard quality control includes comprehensive analytical testing via HPLC, GC, NMR, and MS to confirm identity, purity, and the absence of specified impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. We support development projects with custom purity specifications (e.g., >97%, >98%, >99%) and can align with GMP guidelines for late-stage development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.