Description

4H-1,4-Benzoxazine-4-Acetamide,2,3-Dihydro-2-Methyl-3-Oxo-n-2-Propynyl-(9Ci) is a specialized heterocyclic organic compound with a benzoxazine core, serving as a crucial advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring both acetamide and propynyl functional groups, makes it a valuable building block for constructing complex pharmacophores and functional materials. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science sectors for the synthesis of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor for developing specialty polymers, dyes, and photoactive materials due to its benzoxazine ring system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A versatile building block for methodological studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	4H-1,4-Benzoxazine-4-Acetamide,2,3-Dihydro-2-Methyl-3-Oxo-n-2-Propynyl-(9Ci)
CAS No.	606119-01-1
Molecular Formula	C14H14N2O3
Molecular Weight	258.27 g/mol
Synonyms	N-(2-Propynyl)-2-methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazine-4-acetamide; 2,3-Dihydro-2-methyl-3-oxo-N-2-propynyl-4H-1,4-benzoxazine-4-acetamide; 4H-1,4-Benzoxazine-4-acetic acid, 2,3-dihydro-2-methyl-3-oxo-, 2-propynylamide; 606119-01-1; Benzoxazine acetamide derivative; Propargyl benzoxazineacetamide
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate, ensuring batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.